Ageing is an irremediably universal process, through which our cells reach a state of senescence, which is essentially one of the bases of the ageing process that we can observe when we see an elderly person.
Although growing older is something that no one can avoid, there are lifestyle factors that help to maintain a healthy ageing process and a good functional state.
Among them, we can highlight the following:
- Regular physical exercise and maintaining a moderate level.
- Cognitive stimulation, through study, reasoning, (video-)games, etc.
- A diet rich in antioxidants and essential nutrients, varied and complete.
- Alternative medicine strategies, among which yoga, mindfulness, meditation, etc. can be considered.
- Social relationships. Good personal relationship and social (interpersonal) health is important for healthy ageing.
- Stress management and positive attitude.
- Use of food supplements.
Among these, we find 9 key compounds not to be missed!
Index
Spermidine
You cannot start a list of anti-ageing products without talking about spermidine.
Spermidine is a polyamine whose biological mechanisms related to the ageing process are truly complex. But what is really important to understand is that spermidine, as a key representative of this group of compounds (polyamines), plays a key role in many molecular mechanisms involved in the ageing process and its regulation by dietary supplementation may reduce ageing.
- Spermidine induces autophagy, the dysfunction of which is associated with ageing and the onset of age-related diseases.
- Spermidine regulates cell growth and acts on chemical message initiation and translation factors in cells, which are adversely affected in their normal function over the years.
- Spermidine is implicated in a multitude of metabolomic effects by acting on targets linked to molecular signalling cascades such as Akt/PKB, MAPK, SIRTuin, mTOR, eIF2 initiation factors, etc.

Magnesium
Ageing significantly affects magnesium metabolism:
1. Given the loss of appetite in older people, magnesium intake tends to decrease.
2. Intestinal absorption of magnesium is reduced with ageing.
3. Increased renal elimination of magnesium.
All these factors together contribute to the loss of a healthy magnesium status in the body, which, although often asymptomatic (in mild cases), can contribute to common age-related conditions that may go unnoticed, such as asthenia, sleep disturbances, hyperemotionality and cognitive impairment.
Add highly bioavailable magnesium mineral salts to your diet:
Magnesium Citrate by RawSeries
Collagen
Collagen is the most abundant protein in our body, and ageing has negative effects on this structure.
The loss of elastin and collagen fibres causes older people’s skin to age, leading to the appearance of wrinkles, fine lines and other cosmetic defects.
But not only that, connective tissue forms part of structures such as joints, and its degeneration is one of the factors that helps older people to have more problems associated with bones and joints, including instability and weakness.
At HSN, we have many products with collagen. We recommend that you don’t miss the specific collagen formula for the care of your joints:

Collagen Joint Health by EssentialSeries
Selenium
Selenium is a trace element that acts as an antioxidant and also plays a key role in ageing.
Selenium deficiency is associated with multiple negative conditions of ageing, such as:
- Keshan and Kashin-Beck disorders.
- Oxidative stress.
- Endocrine disorders.
- Immune system disorders.
- Predisposition to infections.
- Chronic inflammation.
- Neurodegeneration.
- Cardiovascular diseases.
- Oncological events.
Selenium is a key element associated with healthy ageing, with a good quality of life. You can find it in HSN in the organic form of Selenomethionine with better absorption and excellent retention in the body, in concentrations of 100 and 200mcg of elemental selenium.

Selenium 200mcg by EssentialSeries
Q10
Ageing causes a marked loss of efficiency of mitochondria, the organelle in cells where processes related to energy release, metabolic regulation and even cell signalling take place.
Some of this functional loss can be attributed to negatively affected coenzyme Q10 metabolism. This process is also associated with age and, indirectly, with the possible use of statin-type drugs for cholesterol control, which are very common in older people and block the body’s systems for producing coenzyme Q10.
Find Coenzyme Q10 100mg and 200mg, and the reduced form of Ubiquinol Kaneka™.

Coenzyme Q10 200mg by EssentialSeries
Nicotinamide adenine dinucleotide
Nicotinamide adenine dinucleotide or NADH is a cellular coenzyme, like Q10, that is closely involved in the body’s oxidation-reduction processes, acting as an important antioxidant agent to protect cells from the senescence process.
NADH is an important coenzyme that contributes to the body’s RedOx balance and positive health effects in the elderly.

Microencapsulated NADH by EssentialSeries
Vitamin D and Vitamin D3
Vitamin D is an extremely important vitamin in older people, as it not only contributes to metabolic and endocrine health, but is a key part of a complex system of calcium metabolism regulation that helps maintain healthy bones.
One of the main consequences of ageing is the loss of bone mineral density, which causes bones to become more brittle as they lose “hardness”; and the loss of this density makes bone fractures in older people a serious problem, especially in bony structures such as the hip, which can increase the risk of morbidity and mortality.
Find vitamin D in the form of cholecalciferol (D3), which is the most bioavailable form, in different concentrations 1000 – 50000 IU, in standard and vegan versions, at HSN.

Vitamin D3 4000IU by EssentialSeries
Vitamin B12
Vitamin B12 is closely related to haematological (blood) and cognitive health.
It is especially key in older people because of their high predisposition to develop anaemias (both iron deficiency and megaloblastic) due to lower consumption of red meat and foods of animal origin in adequate amounts, which are the only sources of bioavailable vitamin B12.

Vitamin B12 by EssentialSeries
Multivitamin
A simple way to ensure adequate nutritional intake in older people, who do not maintain rich and varied diets, is to use a multivitamin. If you are in doubt as you read this article about which vitamin or nutrient to prioritise, let me recommend that you include a multivitamin in your diet.

Daily Two Multivitamin by EssentialSeries.
In addition to those listed above, there are other supplements that may have additional positive properties, for example:
- Curcuminoids from turmeric, or gingerol from ginger may help reduce the state of chronic low-grade inflammation that older people are exposed to due to their biological ageing.
- Evoptogen is a formula with herbal adaptogens that can help to cope with out-of-normal situations that disrupt people’s physical and emotional balance during ageing, increasing resilience.
- Many probiotics, such as the formulas in our Biotics line, help to address factors related to depressed immune systems or intestinal permeability.
- Nutrients such as calcium salts are important for maintaining bone health, and restoring mineral density, allowing bones to regain strength and resilience.
- Compounds such as red yeast rice with standardised monacolin K content are natural supplements for the care of health implications commonly associated with ageing, such as hypercholesterolaemia.
Conclusion
Food supplements play a key role in holistic dietary care, which in turn is key to healthy ageing.
Include a broad spectrum of vitamins and minerals in your diet through the use of multivitamins, and/or specific vitamin/mineral products if you have an increased need for certain nutrients.

Take products such as collagen if your joints are suffering, red yeast rice to maintain your cholesterol levels, and antioxidants such as NADH, PQQ or resveratrol to support the body’s redox balance during the process of loss of efficiency your body faces as it ages.
HSN offers products for all your needs, with all the quality guarantees of the manufacturing process.
Bibliographical references
- Al-Atif, H. (2022). Collagen Supplements for Aging and Wrinkles: A Paradigm Shift in the Fields of Dermatology and Cosmetics. Dermatology Practical and Conceptual, 12(1), e2022018. https://doi.org/10.5826/dpc.1201a18
- Barbagallo, M., Veronese, N., & Dominguez, L. J. (2021). Magnesium in aging, health and diseases. Nutrients, 13(2), 1–20. https://doi.org/10.3390/nu13020463
- Giustina, A., Bouillon, R., Dawson-Hughes, B., Ebeling, P. R., Lazaretti-Castro, M., Lips, P., … Bilezikian, J. P. (2023). Vitamin D in the older population: a consensus statement. Endocrine, 79(1), 31–44. https://doi.org/10.1007/s12020-022-03208-3
- Hernández-Camacho, J. D., Bernier, M., López-Lluch, G., & Navas, P. (2018). Coenzyme Q10 supplementation in aging and disease. Frontiers in Physiology, 9(FEB), 44. https://doi.org/10.3389/fphys.2018.00044
- Minois, N. (2014). Molecular basis of the “anti-aging” effect of spermidine and other natural polyamines – A mini-review. Gerontology, 60(4), 319–326. https://doi.org/10.1159/000356748
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