
HARPAGOPHYTUM (25:1) EXTRACT 400mg (DEVIL'S CLAW)
Highly concentrated extract of devil's claw root. Ratio 25:1 (25x more concentrated than the original raw material). Extract exclusively from the root. Certified species: Harpagophytum procumbens. Extract standardised to 5% harpagosides. Sustainably harvested and cultivated. Formula with vitamin C and copper. Suitable for vegan diets (in vegetable capsules).





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- Harpagophytum extract (Devil's claw).
- High concentration: 25x more concentrated than the native root.
- Standardised to 5% harpagosides - The plant's most characteristic compounds.
- Ethnotraditional plant used in regions of Africa throughout centuries of history.
- HSN formula with Vitamin C and copper in its composition - Maximum effectiveness guaranteed.
- Devil's claw helps to keep joints and tendons flexible.
Table of contents
Quality Devil's Claw Extract at your fingertips
Devil's Claw Extract (25:1) 400mg by EssentialSeries is a food supplement in vegetable capsules developed from a highly concentrated extract of the root of the plant Harpagophytum procumbens (Burch.) DC. ex Meisn. (Pedaliaceae), as the main ingredient of a simple yet effective formula developed with Vitamin C and Copper for their synergistic properties to the extract.
Harpagophytum procumbens is found in regions between 15° and 30° latitude in southern Africa (Namibia, Botswana, South Africa, Angola, and, to a lesser extent, Zambia, Zimbabwe, and Mozambique) (Ihlenfeldt and Hartmann, 1970). The plant typically grows in the red sandy soils of the Kalahari Desert, in areas with low annual rainfall.
Harpagophyte comes from the Greek harpago meaning 'hook' and phytos meaning 'plant', due to the hook shape of its fruits, which is why it is colloquially called devil's claw.
Get to know the Harpagophytum plant
Certified species: 100% Harpagophytum procumbens
Did you know that…
plants of the genus Harpagophytum are colloquially called 'devil's claw' even though they are not of the species procumbens?
However, the scientific research and history of relevant use are specifically associated with this species, not the genus, so products where the commercial term 'devil's claw' is established must be guaranteed to be of species origin.
At HSN, we carry out an exhaustive control of the certified botanical species we use to prepare our extracts. Therefore, we ensure the supply of a 100% Harpagophytum procumbens extract with no other crossbred species that could worsen the physiological properties of the product.
Standardisation to 5% Harpagosides. Guaranteed quality control
Devil's Claw has many naturally occurring compounds, which are traditionally part of its composition and are what give it the properties it has been attributed.
Among the compounds naturally present in devil's claw are:
- Iridoid glycosides.
- Phenolic glycosides (actoside, isoactoside and bioside).
- Harpagoquinones.
- Phenolic acids (caffeic, cinnamic and chlorogenic).
- Flavonoids.
- Phytosterols.
Among all of them, the Iridoid Glycosides stand out, and within this group, there is a type of compound that is the most characteristic of the plant and the one that scientific research has focused on studying as it seems to be the most responsible for the plant's nutritional properties: Harpagosides.
Devil's claw extract by HSN is processed according to the highest quality procedures for the care of the native composition of the plant. This results in a high concentration of functional bioactives among which we ensure a 5% harpagoside content, measured through the use of highly sensitive laboratory analytical methods to ensure low batch-to-batch variability and accurate content.
High concentration per unit - Convenient way of use
HSN extract is 25 times more concentrated than the original root raw material from which it is prepared.
This high concentration allows a single 400mg capsule to store the equivalent of consuming more than 10g of native harpagophytum root.
What's more, each capsule contains 400mg, which is a high concentration considering the density of devil's claw extract. This is why not many companies can offer such a unitary supply and are limited to capsules with 20-50% less concentration.
Our extract is more convenient because, thanks to its high concentration and content, you don't need to take as many capsules a day as with other products. Take just 2 capsules a day and get the full effective dose.
Environmentally friendly harvesting and species protection
Devil's claw is a plant that has been postulated on numerous occasions as a candidate for listing as an endangered botanical species. However, national governments in the regions of Africa where it is harvested have taken commercial sustainability management measures to prevent this.
This doesn't mean that there are no vested interests behind the plant that may cause other producers not to respect the conditions necessary to ensure its sustainability.
At HSN, we only work with raw material producers that ensure respectful cultivation and harvesting, in compliance with public policies for the preservation of the life of the species.
Because there is no Planet B, HSN is doing its part.
100% vegan food supplement. In gelatine-free capsules
Our Devil's Claw extract is suitable for vegetarian and vegan diets as no animal ingredients are used in its composition, including the capsules.
Unlike most other manufacturers on the market, the capsules of HSN food supplements are not made from gelatine but from HPMC, a natural plant cellulose derivative, which results in high-strength vegetable capsules suitable for vegetarian and vegan diets.
Devil's claw is a traditionally used plant loaded with beneficial properties
Plants of the genus Harpagophytum, including procumbens, have been used for centuries by the traditional cultures of different African countries where these plants grow naturally.
Thanks to its characteristic richness in phytocompounds, it has a large number of properties, including its effects on the locomotor system, as it helps to strengthen the body's locomotive system.
This is achieved by helping to maintain joint health and maintain good mobility.
Vitamin C and copper have been added to the formula for this reason, as vitamin C contributes to normal collagen formation for the normal function of cartilage, and copper contributes to the maintenance of normal connective tissue.
In addition, the devil's claw has important virtues associated with the digestive system as it helps support digestion and contributes to digestive comfort.
Recommended for Elderly people
Elderly people are also a common consumer group of devil's claw extract.
Check out Turmeric, Boswellia, and more extracts at HSN. Find out more!
Combine it with other extracts loaded with positive properties!
And with interesting compounds for your goals!
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Bibliography of devil's claw
- Blumenthal, M., & Busse, W. R. (1998). The complete German Commission E monographs. Austin, Texas : Boston: American Botanical Council.
- Denner, S. S. (2007). A Review of the Efficacy and Safety of Devil’s Claw for Pain Associated With Degenerative Musculoskeletal Diseases, Rheumatoid, and Osteoarthritis. Holistic Nursing Practice, 21(4), 203–207.
- Jonasson, P., Halldin, K., Karlsson, J., Thoreson, O., Hvannberg, J., Swärd, L., & Baranto, A. (2011). Prevalence of joint-related pain in the extremities and spine in five groups of top athletes. Knee Surgery, Sports Traumatology, Arthroscopy, 19(9), 1540–1546.
Nutritional FactsHARPAGOPHYTUM (25:1) EXTRACT 400mg (DEVIL'S CLAW) - 120 Veg caps |
daily doseper serving |
Serving size: 1 veg caps | ||
daily dose: 2 veg caps | ||
Servings per container: 120 | ||
Daily amount | |||
---|---|---|---|
Harpagophytum root extract (25:1) (5% harpagosides) (Harpagophytum procumbens) | 800mg | ||
root equivalence | 20000mg | ||
Harpagosides | 40mg | ||
Vitamin C (as ascorbic acid) | 40mg | ||
Copper | 0.3mg | ||
of cupric gluconate | 2.1mg |
NRVs (Nutrient Reference Values) established in Regulation (EU) 1169/2011 of 25 October 2011. †† NRVs are not established on this occasion. |
Ingredients
Harpagophytum extract (25:1, from Harpagophytum procumbens root, 5% harpagosides), vegetable capsule [glazing agent (hydroxypropyl methyl cellulose)], bulking agent (microcrystalline cellulose), anti-caking agent (magnesium salts of fatty acids), ascorbic acid (vitamin C), cupric gluconate.
Warnings
Store in a cool (below 25°C), dry and dark place. Do not exceed the stated recommended daily dose. Keep out of reach of the smallest children. Nutritional supplements should not be used to replace a balanced diet. It is necessary to maintain a varied and balanced diet and a healthy lifestyle. Health claim awaiting European authorization.

How to take HARPAGOPHYTUM (25:1) EXTRACT 400mg (DEVIL'S CLAW) - 120 Veg caps
Take 1 vegetable capsule, 2 times a day with meals.

A satisfied customer says:
Delighted with it.
Fabiola 31/08/2023
I have been using for some years another brand of harpagofito for pain, a few months ago I was told about this brand for the concentration it has and I decided to buy it because there are 2 capsules instead of 3 as almost all, and I was delighted, I noticed an improvement much earlier than with the others I had used.
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A critical customer says:
I have not noticed anything
Marta 26/06/2023
I have spent two months taking the pills and have not noticed anything. I will not buy them again.
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Good product
Juliana 02/09/2025
The truth is that it is very effective. It started to work for me after only a few days. With the cold, joint pains always come and this type of devil's claw is very good for me.
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Good product
Moises 24/08/2025
Good product for the joints, minimizes pain, but if you want greater effectiveness, combine it with Evoflex and it will give you much better results.
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Positive result
Demie 27/07/2025
Positive results to fight inflammation and an aid to reduce joint pain, with antioxidant effect and a good quality-price ratio.
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Anti-inflammatory
Fran rt 11/07/2025
For those of us who suffer from continuous muscular overloads and problems in arms and legs, devil's claw is our natural anti-inflammatory. The concentration is adequate and the effect is sufficient with a single tablet. Highly recommended.
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It works
Arpagofito 06/07/2025
I just started taking it and my chronic knee pains were reduced. Easy to treat, no taste. I will repeat.
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