
HYPERICUM (ST JOHN'S WORT EXTRACT 18:1) 300mg
Authentic St John's wort. St John's wort extract. 18 times more concentrated. 0.3% hypericin. Formula with vitamin B12. 300mg of extract per capsule. Vegan-friendly.




- St John's wort extract.
- Standardised to 0.3% Hypericin.
- 18:1 extraction ratio.
- With vitamin B12.
- Vegan-friendly.
Table of contents
What is St John's wort (St John's wort extract 18:1) 300mg?
St John's wort (St John's wort extract 18:1) 300mg by EssentialSeries is a dietary supplement based on leaf, flower and stalk extract of St John's wort, with vitamin B12.
St John's wort, scientifically known as Hypericum perforatum, is a plant traditionally used in multiple preparations, including juices, dry and liquid extracts, and dyes.
This product is suitable for vegan diets.
Hypericum properties
- St John's wort (Hypericum perforatum) contributes to emotional balance and overall well-being.
- St John's wort (Hypericum perforatum) promotes optimal relaxation.
- St John's wort (Hypericum perforatum) helps support relaxation and mental and physical well-being
- St John's wort (Hypericum perforatum) helps support a healthy sleep.
- St John's wort (Hypericum perforatum) helps promote a positive mood.
- St John's wort (Hypericum perforatum) contributes to a good nerve balance during the menstrual cycle.
- Hypericum perforatum (Hypericum perforatum) helps promote positive mood during menstruation.
- Hypericum perforatum (Hypericum perforatum) tones the body, stimulates mental working abilities, and increases adaptation of the body in extreme and stressful situations.
Vitamin B12
- Vitamin B12 contributes to normal energy metabolism.
- Vitamin B12 contributes to normal nervous system function.
- Vitamin B12 contributes to normal psychological function.
- And vitamin B12 helps to reduce tiredness and fatigue.
Why buy Hypericum Extract by HSN?
High concentration
Hypericum is a widely used plant, especially in regions of indigenous origin such as the United States, North America in general, and Europe and Asia.
However, significant quantities of the plant parts containing the compounds of interest are required, such as hypericin, especially in the branching parts of the plant (in leaves, stems and flowers).
These quantities can't be encapsulated in sufficient amounts to note a beneficial effect, meaning companies that market St John's wort without extracting aren't offering a quality product.
Our St John's wort extract is 18 times more concentrated than its natural state, which means each recommended daily dose of 900mg of extract equates to more than 16 grams of leaves, flowers and stems of St John's wort.
Can you imagine how many capsules you would have to take to consume 16 grams of St John's wort? It's not practical, why is why HSN's extract is the best choice.
With Hypericin
St John's wort contains a unique component called Hypericin, in addition to other similar derivatives such as Hyperforin, but it's hypericin that's the real star of hypericum's composition.
Many plants, especially extracts, lose their hypericin content due to the raw material's processing, such as through concentration, drying, etc. The plant is mistreated and its chemical composition is degraded, hence the importance of standardising the extracts.
Standardisation is the method by which a system for developing a herbal extract is patented, which, through verification by analysis, makes it possible to determine how to achieve the best possible quality.
St John's wort extract by HSN is standardised to 0.3% Hypericin, the main compound responsible for the plant's properties, ensuring its quality is unmatched by other options on the market.
Studied dose
St John's wort is backed by multiple studies that have allowed us to work out the precise dose recommendation to maximise its effects.
Unlike other plant extracts, St. John's wort has a very clear and uniform recommended daily use backed by rigorous scientific literature:
Take 1 x 300mg capsule, of a standardised extract at 0.3% of Hypericin, 3 times a day.
The same dose as we recommend at HSN, from an extract with the perfect properties to make the most of its effects.
Because our R&D department invests a great deal of effort in scientific research to offer you safe and truly effective dietary supplements.
Trust in HSN!
Vegan-friendly
St John's wort extract is suitable for vegan diets.
What can you combine this product with?
You can use it with:
Studies on St. John's wort
- Linde K, Ramirez G, Mulrow CD, et al. St John's wort for depression: an overview and meta-analysis of randomised clinical trials. 1996. In: Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet]. York (UK): Centre for Reviews and Dissemination (UK); 1995-.
- Nicolussi, S., Drewe, J., Butterweck, V., & Meyer zu Schwabedissen, H. E. (2020). Clinical relevance of St. John’s wort drug interactions revisited. British Journal of Pharmacology, 177(6), 1212–1226.
- Butterweck, V. (2003). Mechanism of action of St John’s wort in depression: What is known? CNS Drugs, 17(8), 539–562.
- Linde, K. (2009). St. John’s Wort - An overview. Forschende Komplementarmedizin, 16(3), 146–155.
- Ng, Q. X., Venkatanarayanan, N., & Ho, C. Y. X. (2017). Clinical use of Hypericum perforatum (St John’s wort) in depression: A meta-analysis. Journal of Affective Disorders, 210, 211–221.
- Apaydin, E. A., Maher, A. R., Shanman, R., Booth, M. S., Miles, J. N. V., Sorbero, M. E., & Hempel, S. (2016). A systematic review of St. John’s wort for major depressive disorder. Systematic Reviews, 5(1), 148.
Nutritional FactsHYPERICUM (ST JOHN'S WORT EXTRACT 18:1) 300mg - 120 veg caps |
daily doseper serving |
Serving size: 1 veg caps | ||
daily dose: 3 veg caps | ||
Servings per container: 120 | ||
Daily amount | |||
---|---|---|---|
St. John's wort leaf, flower and stalk extract (18:1) (0.3% hypericin) (Hypericum perforatum) | 900mg | ||
leaf, flower and stalk equivalence | 16200mg | ||
Hypericin | 2.7mg | ||
Vitamin B12 (as methylcobalamin) | 1.1μg |
NRVs (Nutrient Reference Values) established in Regulation (EU) 1169/2011 of 25 October 2011. †† NRVs are not established on this occasion. |
Ingredients
St John's wort extract (18:1, Hypericum perforatum leaf, flower and stalk, 0.3% hypericin), rice flour, vegetable capsule [glazing agent (hydroxypropyl methyl cellulose)], anti-caking agent (L-leucine), anti-caking agent (tricalcium phosphate), maltodextrin, methylcobalamin (vitamin B12).
Warnings
Store in a cool (below 25°C), dry and dark place. Do not exceed the stated recommended daily dose. Keep out of reach of the smallest children. Nutritional supplements should not be used to replace a balanced diet. It is necessary to maintain a varied and balanced diet and a healthy lifestyle. Health claim awaiting European authorization.

How to take HYPERICUM (ST JOHN'S WORT EXTRACT 18:1) 300mg - 120 veg caps
Take 1 vegetable capsule, 3 times a day with meals.

A satisfied customer says:
Amazing
Gracia maría 23/08/2023
I am having hot flashes due to menopause and the summer heat does not help. In the second dose, I have already noticed a great improvement with the nerves and in the last few hours I have hardly noticed any hot flashes. Highly recommended.
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A critical customer says:
Slightly effective.
Skd 28/12/2023
Limited effectiveness, it is true that it induces some mental relaxation and reduces anxiety but the effect is quite difficult to notice and is long term.
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Wonderful
S.O. 06/09/2025
I have really noticed an improvement in my general mood. I don't have as many lows as before but I am more stable. You have to be consistent in the shots but it is worth it.
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Great
Emmely 06/07/2025
I have already recommended it to 2 friends who have very low spirits. For 6 weeks I have been taking a treatment against migraine, which has made me very depressed in just one week.... Since I have been taking yours, in only 5 days I have noticed a great change, my mood is at its peak, thank you very much for making products of such high quality.
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I take it because it is very good for low moods and spring asthenia.
josean 10/05/2025
I take it because it is very good for low moods, spring asthenia. Very easy to swallow capsules, quality, price compared to other brands.
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Effective as always St. John's wort
Valeria 19/03/2025
It is a natural antidepressant, that the time of exposure to it will condition its effectiveness, if prescribed antidepressants we need a minimum of one month to see its effects so that the receptors are sensitized, this is an extract that will need more. But I must say that it works! Be careful if you take medication or oral contraceptives, it is one of the herbs that has more interactions.
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A real discovery
Javi 21/12/2024
The truth is that I started taking it because sometimes I was a little sad and the truth is that it helps to be more positive and not think so much, I had read that it takes time to take effect but I noticed it from the first day.
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