NATTOKINASE 2000FUs
Pure nattokinase enzyme from natural Natto origin (fermented soy). Guaranteed activity: 2000 fibrinolytic units – the equivalent of more than 100 g of quality Natto! With vitamin B1 - supports heart function. Made from soy free of genetically modified organisms. Certified vegan-friendly product.
IRON BISGLYCINATE Ferrochel™ (30mg IRON)
BEETROOT POWDER
COENZYME Q10 100mg + BioPerine®
COLLAGEN SUPER BEAUTY *
PREMIUM OMEGA-3 TG (IFOS) 1000mg
LYCOPENE 15mg + FLAX SEED OIL
UBIQUINOL (Kaneka Ubiquinol™) 100mg
- Pure natural Nattokinase isolated from fermented soy natto extract.
- Provides 2000 authentic Fibrinolytic Units per capsule. High fibrinolysis activity.
- With Thiamine (Vitamin B1) in hydrochloride form. A high bioavailability form.
- Supports cardiovascular activity and heart health thanks to the thiamine content.
- More durability! 120 vegetable capsules per container. Lasts 4 months.
- Now in delayed-release vegetable capsules for better bioavailability!
- Made with extract from fermented soybeans free of Genetically Modified Organisms.
- HSN’s Nattokinase is certified as vegan-friendly and 100% GMO-Free.
Table of contents
What is Nattokinase and why use it

NattoKinase 2000FUs from EssentialSeries is a dietary supplement in delayed-release vegetable capsules made from the pure enzyme naturally produced by Lactobacillus that ferment soy to create natto, called Nattokinase, with thiamine.
Nattokinase is a protein naturally produced when soy is fermented. Fermented soy foods are common in many Asian regions, with the most well-known in the West being Tempeh and Natto. Nattokinase gets its name from natto, where it was first found.
Nattokinase 2000 FUs is made exclusively from natto produced with soy certified as 100% free of Genetically Modified Organisms, a hugely important factor when considering soy as a quality product.
Why is HSN’s Nattokinase 2000FUs unique?
Nattokinase is an enzyme practically found only in soybeans fermented with food-grade bacteria: Lactobacillus.
Of course, it can be produced from sources treated with Genetically Modified Organisms, and it could be chemically synthesized, but at HSN we prefer to get our compounds from natural sources like soy extract.
You’re looking at a top-quality product of completely natural origin.
Guaranteed content. 100% pure with no traces of origin
Our Nattokinase is certified and tested as free from starting soy, and in our latest raw material upgrade we’ve even eliminated allergen traces from the source, so it contains no soy compounds.
This means our high-activity Nattokinase is pure, even though it comes from a natural source, we’ve isolated the enzyme from soy extract to the max to provide a high concentration per extract unit, with guaranteed high quality and activity.
Still, Nattokinase is not suitable for people allergic to soy.
100% GMO-free. Both in the enzyme and the original soy
Did you know that over 90% of soy grown worldwide contains genetically modified organisms?
At HSN we don’t want to use GMOs just to use cheaper raw materials, and of course, we’re committed to using quality raw materials. We recommend checking out our strategies at the following link.
For all these reasons, we’ve chosen to use extract from soybeans certified as 100% GMO-free in cultivation and production.
We’re the exception that proves quality! Trust HSN for your daily dietary supplementation.
Natural origin. Extract from optimally grown soy
The soy used has been grown considering all aspects needed to get the best possible quality harvest. A warm environment was maintained with temperatures between 20 and 30ºC, with mixed indoor/outdoor growth as needed.
The cultivated soil is alluvium with high organic content, optimal for growing top-quality soy.
At HSN we control the production process of our raw materials from the very start.
Made from natto fermented under controlled conditions with certified safety
Natto is a food made from soybeans fermented in controlled environments with the probiotic (food-grade) bacterium Bacillus subtilis.
This production method dates back to Buddhist times, when monks developed this fermentation system to consume soy longer and with added nutritional benefits.
The natto production process is delicate and must be closely controlled to ensure not only its quality (and that the Nattokinase it produces is functional) but also its safety (and that no secondary reproduction of Lactobacillus natto occurs).
The quality of HSN’s natto used for extraction and subsequent isolation of naturally produced Nattokinase is supreme; it’s natto generated from inoculation, fermentation, and refrigeration of soy following quality and safety criteria firmly established by the world’s most reputable food science researchers.
High fibrinolytic activity: 2000 Fibrinolytic Units (FU) per capsule
The amount of Nattokinase in natto varies, ranging from 1400 FUs per serving up to 2000 Fibrin Degradation Units.
A serving of natto is about 50–100 g, and that amount is significant, making it extremely hard to consume for people not used to fermented soy since it has a strong, challenging flavor.
HSN’s Nattokinase enzyme provides the daily fibrinolytic activity amount of this enzyme in just one capsule — it doesn’t get more convenient than this!
Of course, it doesn’t have natto’s taste or smell, which is great for people who don’t enjoy fermented soy; and the amount of Nattokinase provided equals consuming almost 100 g of high-quality natto (possibly more if cultivation and fermentation conditions aren’t optimized) according to research from the Japanese scientific journal 'Food Science'.
HSN delivers high-concentration Nattokinase with guaranteed high fibrinolytic activity.
With thiamine, an essential vitamin with synergistic activity. The best formula at HSN!
Thiamine, also known as vitamin B1, is an essential water-soluble nutrient, especially found in meats, fish, and dairy. This vitamin is nutritionally indispensable, meaning it must be consumed in sufficient amounts through diet to avoid deficiency that risks health.
HSN’s Nattokinase contains a significant amount of vitamin B1 because it has synergistic activity important for product development, notably supporting normal heart function.
This vitamin makes Nattokinase an ideal supplement for cardiovascular system function. Try it and see for yourself!
Unique properties of HSN’s formula

Nattokinase has been used for centuries by followers of the Buddhist religion.
Over time, natto consumption spread throughout Asia to become a common food, considered a staple often found in the daily diet of Japanese or Korean people.
Many researchers have shown interest in natto’s association with beneficial properties, attributing these to Nattokinase, though research is still ongoing:
- Nagata, C., Wada, K., Tamura, T., Konishi, K., Goto, Y., Koda, S., Kawachi, T., Tsuji, M., & Nakamura, K. (2017). Dietary soy and natto intake and cardiovascular disease mortality in Japanese adults: the Takayama study. The American journal of clinical nutrition, 105(2), 426–431.
- Chen, H., McGowan, E. M., Ren, N., Lal, S., Nassif, N., Shad-Kaneez, F., Qu, X., & Lin, Y. (2018). Nattokinase: A Promising Alternative in Prevention and Treatment of Cardiovascular Diseases. Biomarker insights, 13, 1177271918785130.
This supplement is ideal for people looking after cardiovascular health, as its thiamine content helps normal heart function.
Is this supplement for me?
Nattokinase is an important enzyme rarely found in Western diets, practically nonexistent except in select circles consuming Eastern fermented products.
Nattokinase is perfect for:
- Ultra-endurance athletes who undergo many hours of training with vascular load.
- Older adults and people on high-fat diets with low vegetable intake.
And as always! Anyone wanting the best Nattokinase option on the market: quality, guaranteed safety, high concentration, and proven activity. At HSN.
Recommended combinations by HSN experts:
Nattokinase has a commonly recommended supplement combo perfect for those seeking the best product stack. Take note!
Nattokinase + Vitamin B3 Flush-Free + Bromelain.
And all this is ideal if you combine it with a natural beetroot juice, available in powder form for better preservation and longer shelf life at room temperature. Convenient, clean, and versatile!
Scientific research backing Nattokinase
- Chen, H., Chen, J., Zhang, F., Li, Y., Wang, R., Zheng, Q., … Lin, Y. (2022). Effective management of atherosclerosis progress and hyperlipidemia with nattokinase: A clinical study with 1,062 participants. Frontiers in Cardiovascular Medicine, 9, 964977.
- Weng, Y., Yao, J., Sparks, S., & Wang, K. Y. (2017). Nattokinase: An oral antithrombotic agent for the prevention of cardiovascular disease. International Journal of Molecular Sciences, 18(3).
- Gallelli, G., Di Mizio, G., Palleria, C., Siniscalchi, A., Rubino, P., Muraca, L., … Gallelli, L. (2021). Data recorded in real life support the safety of nattokinase in patients with vascular diseases. Nutrients, 13(6).
- Kurosawa, Y., Nirengi, S., Homma, T., Esaki, K., Ohta, M., Clark, J. F., & Hamaoka, T. (2015). A single-dose of oral nattokinase potentiates thrombolysis and anti-coagulation profiles. Scientific Reports, 5, 11601.
- Chen, H., McGowan, E. M., Ren, N., Lal, S., Nassif, N., Shad-Kaneez, F., … Lin, Y. (2018). Nattokinase: A Promising Alternative in Prevention and Treatment of Cardiovascular Diseases. Biomarker Insights, 13, 1177271918785130.
Nutritional FactsNATTOKINASE 2000FUs - 120 veg caps |
| daily doseper serving |
| Serving size: 1 veg caps | ||
| daily dose: 1 veg caps | ||
| Servings per container: 120 | ||
| Daily amount | |||
|---|---|---|---|
| Nattokinase | 2000 FUs / 30mg | ||
| fermented soy extract | 100mg | ||
| Vitamin B1 | 0.3mg | ||
| thiamine hydrochloride | 0.4mg | ||
| NRVs (Nutrient Reference Values) established in Regulation (EU) 1169/2011 of 25 October 2011. †† NRVs are not established on this occasion. |
Ingredients
Rice flour, fermented soy extract [nattokinase (20000 FUs/g)], delayed-release vegetable capsule [coating agent (hydroxypropylmethylcellulose), gelling agent (gellan gum)], anti-caking agent (magnesium salts of fatty acids), L-leucine, anti-caking agent (tricalcium phosphate), thiamine hydrochloride (vitamin B1).
Warnings
Store in a cool (below 25°C), dry and dark place. Do not exceed the stated recommended daily dose. Keep out of reach of the smallest children. Nutritional supplements should not be used to replace a balanced diet. Persons taking medication should consume the product only under medical supervision. This food supplement should only be consumed by adults, excluding pregnant and lactating women. It is necessary to maintain a varied and balanced diet and a healthy lifestyle. Health claim awaiting European authorization.
How to take NATTOKINASE 2000FUs - 120 veg caps
The product reviews and opinions published reflect only the customers’ views and experiences. HSN does not verify or endorse such comments or claims, and is not responsible for the content provided in the reviews. Statements regarding food supplements have not been evaluated by the EFSA (European Food Safety Authority) and are not intended to diagnose, treat, cure, or prevent any disease or medical condition.
The product reviews and opinions published reflect only the customers’ views and experiences. HSN does not verify or endorse such comments or claims, and is not responsible for the content provided in the reviews. Statements regarding food supplements have not been evaluated by the EFSA (European Food Safety Authority) and are not intended to diagnose, treat, cure, or prevent any disease or medical condition.
-
Good nattokinase
Lia spingola 09/02/2026
Good Nattokinase, I bought it on the recommendation of my integrative medicine doctor and it did what it promised in terms of preventing clots, I'm very pleased.
Show original languageWas the review helpful? Be thefirst one to rate the review -
Great
Fran 04/06/2025
This nattokinase I can confirm that it has helped me lower my blood pressure. Highly recommended. Unbeatable price.
Show original languageWas the review helpful? Be thefirst one to rate the review -
Improved circulation
Lara 16/05/2025
I bought it because my naturopath recommended it to me to improve circulation and avoid clots that can put my body tissues and my health at risk. Good amount of nattokinase, I am happy with my choice.
Show original languageWas the review helpful? Be thefirst one to rate the review -
TOP
Laurie 14/05/2025
Very good product. Good packaging. I'll buy again. Good value for money.......
Show original languageWas the review helpful? Be thefirst one to rate the review -
Good value for money
Carol 21/04/2025
I have switched to this brand of Nattokinasa and the truth is that it is working quite well, the quality price is pretty good. It is not the best on the market by far, but it does its job! I will continue to buy it (unflavored).
Show original languageWas the review helpful? Be thefirst one to rate the review
No reviews found with filters applied.
{title}
{nickname-date}
{detail}
{review-link}
EN - EUR
Albania
Austria
Belgique
Bosnia and Herzegovina
Bulgaria
Canadá
Chile
Chipre
Corea (la República de)
Croacia
Czechia
Denmark
Deutschland
Eslovaquia
Eslovenia
Estonia
Finland
France
Greece
Hungary
Iceland
Ireland
Islas Feroe
Italia
Japan
Latvia
Lithuania
Luxembourg
Macedonia
Malta
Marruecos
Mónaco
Montenegro
Netherlands
Noruega
Poland
Portugal
Romania
Schweiz
Serbia
South Africa
Suecia 
