EpiCor® is a unique postbiotic obtained through a patented fermentation process of Saccharomyces cerevisiae yeast. Its main benefit lies in the robust support it offers to the immune system, helping to keep the body’s natural defences especially active and ready during seasonal changes, times when the immune system may be more vulnerable.
This natural ingredient has shown in various studies its ability to modulate and strengthen the immune response.
It works by balancing defences and contributes to a lower incidence of common symptoms associated with colds, flu, and nasal discomfort caused by allergies, often triggered by seasonal changes.
What is EpiCor® and How Does It Work in Your Body?
Unlike probiotics (live microorganisms) and prebiotics (fibres that feed them), postbiotics are bioactive compounds generated after microbial fermentation. In the case of EpiCor®, this process is carefully controlled to obtain a standardised and potent profile of beneficial metabolites.
During fermentation, S. cerevisiae produces a complex matrix of nutrients and functional compounds that have a positive effect on the body without containing live microorganisms.
Unlike probiotics, which are live microorganisms, or prebiotics, which are fibres that feed these microorganisms, EpiCor® is a fermented product that contains the beneficial compounds released by the yeast during fermentation, as well as components from the now-inactive yeast itself.
These components interact with the immune system from the gut, helping to maintain the body’s balance and defensive response, which is particularly useful during seasonal changes.
The production process of EpiCor® is unique and meticulously controlled. It starts with baker’s yeast (Saccharomyces cerevisiae), which is grown in a nutrient-rich medium. Under specific anaerobic stress conditions (lack of oxygen) and other controlled factors, the yeast begins a fermentation process. During this fermentation, the yeast produces a wide variety of bioactive compounds.
Once the fermentation is complete, the yeast biomass and the metabolite-rich broth undergo a gentle, patented drying process. This step is essential to preserve the integrity of the formed bioactive compounds, resulting in the dry powder that is EpiCor®.
Action in the Body
EpiCor® acts in the body in several ways to support health, mainly targeting the immune system and gut health:
- First line of defence support: helps increase levels of Secretory Immunoglobulin A (sIgA), a crucial antibody found in mucous membranes (nasal, oral, intestinal) that acts as the first barrier against pathogens.
- Immune cell activation: stimulates the activity of Natural Killer (NK) cells, which are vital for quickly eliminating infected or abnormal cells. It can also modulate the activity of other immune cells like T and B lymphocytes.
- Antioxidant action: the various compounds present in EpiCor® have antioxidant properties, helping neutralise free radicals and reduce oxidative stress, which supports overall immune function.
- Immune response balance: instead of simply ‘stimulating’ the immune system, EpiCor® seems to help balance it. This means it may enhance defences when needed and also regulate an excessive immune response, such as in certain allergic sensitivities, helping reduce nasal congestion in people with seasonal allergies.
- Gut health and prebiotic-like effect: although it is a postbiotic, studies suggest EpiCor® may also act like a prebiotic, promoting the growth of beneficial gut bacteria. A healthy gut microbiome is closely linked to a strong immune system.

Difference with Other Postbiotics/Probiotics
- Probiotics: are live microorganisms that, when consumed in adequate amounts, provide a health benefit to the host. They must survive passage through the gastrointestinal tract and colonise the gut to be effective.
- Postbiotics: are preparations of inanimate microorganisms and/or their components that provide a health benefit to the host. EpiCor® fits into this category. As it is inanimate, it offers advantages in stability and safety, especially for individuals with compromised immune systems. Its effectiveness is not dependent on cell viability.
- Other postbiotics: while other postbiotics are derived from different bacterial strains or fermentation processes, EpiCor® is distinguished by its specific fermentation process using Saccharomyces cerevisiae and the unique resulting metabolite profile. The clinical research supporting EpiCor® focuses on this specific composition and its demonstrated effects.
Benefits of Fermented Dried Yeast EpiCor®
- ?Science-backed immune system support: six human clinical trials have shown that EpiCor® supports the normal functioning of the immune system. These include studies carried out in both winter and spring, as well as research into its role as an immunomodulator.
- ?Gut microbiota balance: a human study involving 80 participants found that consuming EpiCor® for six weeks can positively influence gut microbiota composition. Additionally, in vitro digestion models confirmed its beneficial action within the gut environment.
- ?Immune support during spring: a clinical trial with 96 individuals showed that EpiCor® supports immune and nasal wellbeing during times of seasonal environmental stress, such as pollen exposure.
- ?Enhanced winter defences: two clinical studies involving 116 participants found that taking EpiCor® daily for 12 weeks helps maintain a balanced immune response to winter-specific challenges.
Why Choose EssentialSeries EpiCor® Over Other Alternatives?
When it comes to supporting your immune system, not all options are the same. HSN’s EpiCor®, part of the EssentialSeries range, stands out thanks to its commitment to quality, science, and transparency.
- ⭐Choosing this product means opting for a safe, effective, and responsible formula designed with your daily wellbeing in mind.
Here’s why it’s a superior choice:
- National and certified manufacturing: produced in Spain under stringent quality standards.
- Evidence-based: the dosage and format are based on clinical studies supporting the efficacy of EpiCor® as an immune aid.
- Stable, ready-to-use formula: its vegetable capsule format ensures easy intake, without the need for refrigeration or prior preparation.
- Suitable for all: 100% vegan, free from gluten, lactose, soy, and other common allergens. Ideal for those with specific dietary needs or following a plant-based lifestyle.
- Purity commitment: free from unnecessary additives, colourings, or artificial fillers. Just what you need, nothing more.
How to Take EpiCor® 500mg and Usage Tips
At HSN, we recommend taking 1 vegetable capsule once daily, with or without food. This dosage allows for continuous use without the need for breaks.
- ?Many people prefer to use the capsule’s contents directly—just open it, pour the contents into a glass of water or your favourite drink, and take it.

Fermented Dried Yeast (EpiCor®) 500mg from EssentialSeries
Sources
- https://epicorinfo.com/
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