MAGNESIUM L-THREONATE (Magtein®)

Magtein® Magnesium L-Threonate – The magnesium that thinks of you

Magtein® Magnesium L-Threonate from EssentialSeries is a magnesium-based dietary supplement.

Magtein® is the patented form of magnesium L-threonate designed to make the most of the neurocognitive properties of magnesium as a mineral. The goal of magnesium threonate is clear: support normal nervous system function and help reduce tiredness and fatigue. Thanks to its properties, Magtein® ensures magnesium works at its best in the nervous system, compared to other conventional salts like bisglycinate or citrate.

When the goal is the mind, the form matters. Magtein® makes the difference.

Why threonate is different

L-threonic acid is a natural metabolite of vitamin C that acts as a transporter. When it binds to magnesium, it creates a complex with affinity for nervous tissue, something other mineral salts can’t achieve to the same extent.

This design allows the nutritional properties of magnesium on the nervous system to be the most notable focus of activity, making Magtein® the best choice when you want to supplement your diet with magnesium for these purposes.

Magtein® quality – Discover it

Magtein® is a patent developed by ThreoTech LLC with unmatched controls for purity, identity, and stability. Its production is protected to guarantee the same composition in every batch of raw material.

Optimal dosage – 2000 mg of Magnesium L-Threonate

Each dose (3 vegetable capsules) provides 2000 mg of Magtein®, equivalent to 144 mg of elemental magnesium. This dosage has been defined by HSN’s R&D experts to maximize magnesium’s activity on normal nervous system function with maximum digestive tolerance, in the most practical way.

Key benefits of magnesium

• Helps reduce tiredness and fatigue.
• Contributes to electrolyte balance.
• Contributes to normal energy metabolism.
• Supports normal nervous system and muscle function.
• Contributes to normal protein synthesis and normal psychological function.
• Helps maintain normal bones and teeth.
• Participates in the cell division process.

Clean label: HSN purity and quality

At HSN, we have an ethical commitment to developing “clean label” formulas. Our magnesium threonate comes with vegetable capsules (no gelatins) and a minimal amount of additional ingredients, no colorants or unnecessary additives, and 0% use of aesthetic ingredients. It’s 100% vegan, allergen-free, and non-GMO.

Practical integration into your day

The daily dose of 3 capsules, taken all at once, is perfect for enjoying magnesium threonate with maximum convenience. You can take them with or without food, although taking them with a meal may improve magnesium’s digestive tolerance.

How to get the most out of magnesium threonate?

Magnesium’s nutritional support is achieved with continued use: consistency is key for magnesium to gradually accumulate in the nervous system and support its normal function. It’s important to maintain an adequate mineral status in the body, and if your diet isn’t naturally rich in magnesium, magnesium threonate is ideal to complement it.

Advantages over other mineral salts

Oxide, citrate, or bisglycinate are common magnesium mineral salts useful for improving general mineral status, but they are not as specifically linked to neurological and psychological functions. Magtein®, as the patented form of magnesium threonate, is: its structure allows you to make the most of its properties.

If your goal is to support your nervous system and neurological health by supplementing with magnesium, L-threonate is the first choice.

Digestive tolerance of Threonate: Excellent

The balance between threonate and elemental magnesium translates into good tolerance, without the laxative effects that other salts with lower bioavailability may cause at high doses.

Who is it ideal for?

People with high mental demand (students, professionals, exam takers, gamers, or chess/poker players) and those looking for general nervous system support or daily help for psychological function.

Smart synergies – What to combine it with?

Magnesium threonate can be combined with choline or caffeine if you’re a student or seeking cognitive support.

It can also be combined with electrolytes or creatine if you use magnesium threonate for sports purposes or as comprehensive support.

Quality commitment – Magtein® × HSN

We use Magtein® raw material because it’s one of the most internationally recognized patents for quality and transparency in production.

Frequently asked questions (FAQ)

Why choose Magtein® over other threonates?

Magtein® is the only patented form of L-threonate with patented backing and specific trials in targeted fields, ensuring undeniable quality with the highest standardization of the production process.

Is a dose of 144 mg of elemental magnesium enough?

Yes. With magnesium threonate, unlike other salts, the dose focuses on the complete salt rather than just its elemental content. Still, 144 mg of elemental magnesium is a relevant dose coming from 2000 mg of magnesium threonate, an optimized daily dose.

When do results show up?

It depends on the previous magnesium status and other factors. The scientific studies evaluating magnesium threonate’s potential usually have an intervention period between 8 and 12 weeks, so this is a good reference for when to expect full nutritional support from daily magnesium use.

A summary to have everything handy

• Main ingredient: Magtein® (magnesium L-threonate) with registered patent.
• Daily intake: 2000 mg of Magtein® = 144 mg of elemental magnesium.
• Goal: normal nervous system function and normal psychological function.
• Development: clean label, vegan, non-GMO, and allergen-free.

Scientific bibliography

• Zhang, C., Hu, Q., Li, S., Dai, F., Qian, W., Hewlings, S., Yan, T., & Wang, Y. (2022). A Magtein®, Magnesium L-Threonate, -Based Formula Improves Brain Cognitive Functions in Healthy Chinese Adults. Nutrients, 14(24), 5235.
• Hausenblas, H. A., Lynch, T., Hooper, S., Shrestha, A., Rosendale, D., & Gu, J. (2024). Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial. Sleep Medicine: X, 8, 100121.
• EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) (2024). Safety of magnesium l-threonate as a novel food pursuant to regulation (EU) 2015/2283 and bioavailability of magnesium from this source in the context of Directive 2002/46/EC. EFSA Journal, 22(3), e8656.
• Fu, C., Huang, L., Lian, C., Yue, J., Lin, P., Xu, L., Lai, W., Gao, C., Li, C., & Long, Y. (2025). Effects of long-term magnesium L-threonate supplementation on neuroinflammation, demyelination and blood-brain barrier integrity in mice with neuromyelitis optica spectrum disorder. Brain Research, 1846, 149234.
• Patel, V., Akimbekov, N. S., Grant, W. B., Dean, C., Fang, X., & Razzaque, M. S. (2024). Neuroprotective effects of magnesium: implications for neuroinflammation and cognitive decline. Frontiers in Endocrinology, 15, 1406455.