Creatine Ethyl Ester, What is it Used for?

Creatine Ethyl Ester, What is it Used for?

Creatine continues to lead the ranking of supplements that help us achieve the best results. This supplement is particularly interesting to gain muscle strength and resistance. But, what about Creatine Ethyl Ester?

If you check the supplementation protocol of almost any athlete, you are surely going to find creatine.

However, there are some versions of creatine that are trying to beat the original. Above all, the manufacturers are taking advantage of new absorption systems by combining certain substances with the active ingredient.

What is Creatine Ethyl Ester?

Creatine is one of the most popular supplements at the moment. Its chemical name is methyl guanidine-acetic acid and it is made up of arginine, methionine and glycine.

For example, creatine ethyl ester is one of those improved versions of creatine. Up until now, it is the most sold type of creatine.

What is CEE?

Take creatine monohydrate and add an ester to it, there you have Creatine Ethyl Ester (CEE). To put it simply, esters are organic compounds that result from a process known as esterification. Said process combines alcohol and carboxylic acid to form an ester.

This ester that binds to creatine significantly improves its absorption. Therefore, we will need less creatine monohydrate to obtain the same results.

UNeMed from the University of Nebraska Medical Center developed, patented and licensed CEE or Creatine Ethyl Ester.

Uses of the Ethyl Ester

It is a byproduct of creatine monohydrate (keeping reading) which is used to support the athletic performance in demanding sports and physical activities.Creatine Ethyl Ester and Sport Activities

Moreover, it is helps to gain muscle and weight in disciplines like bodybuilding. Although anyone can use it in order to improve his or her body composition.

Creatine supports the ATP (Adenosine Tri-Phosphate) energy system or phosphagen system. In fact, it is specially useful for explosive and anaerobic activities: weightlifting, running and sprinting, jumping…

The purpose of creatine supplementation is increasing the amount of phosphocreatine (PCr) in the muscles

Storage of muscle phosphocreatine

Our body uses said molecule as energy during muscle contractions in high intensity exercises.

Without any doubt, creatine is the second most popular sport supplement in the market after Whey Protein. Its benefits for the performance have been proven over and over again. That is why it has become the favorite supplement of many athletes.

What are the Properties of Creatine Ethyl Ester?

There are two reasons why we add an ester to creatine monohydrate. First of all, we improve its absorption and prevent the swelling and dehydration. These two side effects are usually associated with the monohydrate.

Creatine and Training

Those athletes who have not experienced any improvements from taking creatine monohydrate tend to give Ethyl Ester a try.

Another key difference between these two types of creatine is their transport mechanism. Creatine monohydrate is a semi-lipophilic product, which means that it uses fat. The esterification of substances increases its lipophilic features – therefore, CEE will use fat more efficiently to cross the cell wall and produce its effects.

Consequently, we will also need a lower dose of CEE (due to its higher efficiency), but the absorption rate will be even higher… according to the theory.
Moreover, it also has the following potential advantages:
  • No loading phase required
  • Less fluid retention (“bloated” effect)

Does Creatine Ethyl Ester only have Advantages?

There are not many studies about CEE, and the ones about the monohydrate focus on supporting its benefits. One of the most important points of creatine ethyl ester is precisely its degree of utilization.

The researchers carried out the following study: “The effects of supplementation with creatine ethyl ester combined with a heavy resistance training on body composition, muscle performance and levels of serum and muscle creatine levels”.

It assessed the total amount of creatine ethyl ester that our body uses and how much is broken down into creatinine. This substance is a waste product of creatine.

The conclusions of the study were:

“Since creatine ethyl ester supplementation increased the serum creatinine levels considerably throughout the study without a significant increase in total serum and muscle creatine content, we conclude that most of the creatine ethyl ester was being broken down in the gastrointestinal tract after its intake”.

Despite this result, a significant number of athletes use and will continue to use creatine ethyl ester supplements, because they do provide benefits after all

How to take Creatine Ethyl Ester?

CEE is usually available as hydrochloric acid (CEE HCl) and it comes in capsules or tablets. The recommended dose will depend on the manufacturer, but the general dose tends to be 3-6g a day.



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Creatine Ethyl Ester Review

Better absorption - 100%

Higher creatinine levels - 98%

Better muscle performance - 96%

Improved athletic performance - 100%


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About Melanie Ramos
Melanie Ramos
Melanie Ramos uses the HSN Blog to share the latest information and content, so that all those readers who want to learn.
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