Hydrolyzed Whey Protein

Hydrolyzed Whey Protein

Hydrolyzed Whey Protein or Whey Protein Hydrolyzate (WPH) has a distinguishing feature at a molecular level when compared to the rest of the existing proteins: they are hydrolyzed, which means that they have undergone a hydrolysis or molecular segmentation process, which results in a pre-digested protein with a percentage of peptides.

What is Hydrolyzed Whey Protein or WPH?

The hydrolysis is a manufacturing technique that “imitates” the digestive process which would take place in our stomach if we ate a solid protein source, or even Whey.

Protein shake and jump ropeHydrolyzed whey protein is a pure protein, without fats nor sugars, that makes a perfect protein supply before or after post-workout, without causing any stomach discomfort.

Thanks to this advanced processing we obtain a protein with a series of benefits, like a fast absorption rate, which means that it is completely digestible by anyone and its nutritional composition supports the synthesis of proteins.

How does our body absorb proteins?

All proteins are made of amino acids chains. Said links are formed by two or more amino acids, which result in: di or tri-peptides, or tetra or oligo-peptides.

When our digestive system receives the protein, regardless of the source, it will have to proceed by breaking down or fracturing these amino acids links that form the protein. This is done through the secretion of enzymes, in order to absorb and transport them to the tissues of the body through the blood flow.

Our body absorbs proteins as peptides in the intestine, particularly di and tri-peptides.

That is why Hydrolyzed Protein is the most effective format in terms of absorption because they considerably improve the digestion.

Types of Hydrolyzed Proteins

The WPH types come from protein sources that result from the hydrolysis process, for instance:

  • Hydrolyzed Whey Protein Concentrate
  • Hydrolyzed Whey Protein Isolate
  • Hydrolyzed Casein Protein

The hydrolysis is a predigestion method, the following step is to obtain the protein source that will be processed. From this information we can deduce that the hydrolyzates from a concentrate or isolate will preserve the same features:

  • Percentage of protein
  • Amounts of fat and lactose
  • Spectrum of protein fractions

The third distinctive point is the degree of hydrolysis, in other words, the concentration of predigested peptides contained within the protein. The higher the hydrolysis degree, the higher the absorption rate.

Protein fractions in Hydrolyzed Proteins

When the source of protein that will be used to obtain the hydrolyzate has a high percentage of bioactive peptides or protein fractions, we will be able to enjoy the benefits that they provide.

A denatured protein is one that has not been subjected to certain processes, such as ionic exchange, the use of chemicals, or high temperatures that can change its molecular structure, breaking down the protein fractions.

The clearest choice will always be to choose proteins that have not undergone such processes, which is the case of an hydrolyzed protein which keeps all its characteristics in order to improve human health:

  • Anti-inflammatory
  • Strengthens the immune system
  • Has anti-microbial, anti-viral, and anti-bacterial properties
  • Improves the absorption and transport of iron through the body

These protein fractions are:

  • Lactoferrin
  • Glycomacropeptide
  • Immunoglobulins
  • Alpha-lactalbumin
  • Beta-lactalbumin
  • Lactoperoxidase

Hydrolyzed Proteins and Protein Synthesis

Due to the fast absorption rate of WPH, it is going to trigger a sudden increase of all the amino acids present in the bloodstream, which is known as a hyperaminoacidemia, and its main benefit is the stimulation of protein synthesis.

The WPH aminogram tends to be rich in EAAs (essential amino acids) and BCAAs (branched chain amino acids).

Complete proteins are those that provide the entire aminogram, both essential and non-essential without any deficit, so that the organism has the proper building material for tissue regeneration.

One of the BCAAs that we can find is the L-Leucine amino acid, which is important due to its ability to stimulate the protein synthesis by means of a metabolic pathway called mTOR.

Benefits of Hydrolyzed Whey Protein

Ultra-fast Absorption

This ability is intrinsic to all Hydrolyzed Proteins and it perfectly coincides with its task as a pre or post-workout protein intake, which does not cause any digestive problem, providing a quick gastric emptying, which allows the individual to consume successive meals efficiently.


Another feature of some WPHs, specially if they come from Whey Protein Isolate, is that lactose intolerant people can benefit from them without any issues, which guarantees an optimal digestion and later absorption of the amino acids, avoiding the allergic contraindications.

Nitrogen Balance

WPH allows us to discharge the amino acids in the bloodstream faster than any other source, which changes the state of the catabolism to anabolism, which is also known as Nitrogen Balance. This process favors the synthesis of proteins, since at that moment there will be a higher rate of complete amino acids compared to those which are broken down.

Glycogen Recharge

The process of recharging glycogen can be carried out by WPH, since it stimulates the increase of insulin without causing any negative impact on the health markers.

The consumption of WPH produces the translocation of GLUT4, the muscular glucose transporters, which enhances the delivery of insulin to the muscle cells and helps to avoid its accumulation in the fat adipocyte.

Muscle Recovery

Following on from the previous point, we can conclude that if our energy capacity is improved (muscle energy support), our recovery will also be improved. Additionally, it will also improve the athletic performance and the efficiency of each workout session.

Let’s not forget that each workout session produces an alteration of the homeostasis, but the organism has a number of resources that can be used to return to its basal state, to intervene by using the necessary nutrients, which will shorten the recovery period. But what is even more important, we will be in a much better state when we have to face the following workout sessions.

Appetite Control

One of the protein fractions that is most abundant in WPH is Glycomacropeptide, which has the ability to produce more satiety. This is due to its effect on the regulation of ghrelin, a hormone involved in the physiological mechanisms of postpandrial satiety, among others.

How and when should we use Hydrolyzed Proteins?

Hydrolyzed Proteins can help to meet the daily protein requirements, and given their particular properties, the most advisable times to consume them are:

  • On an empty stomach
  • Before training
  • After the workout

How can we combine Hydrolyzed Proteins?

In order to avoid the loss of the properties obtained through the hydrolysis process as much as possible, we can mix or combine WPH with, for example, a carbohydrate, in order to slow down the gastric emptying. The best choice for that would be to consume carbohydrates during the workout or physical activity and then finish with an supply of WPH, or even as a pre-workout.

On the other hand, we can also combine WPH with elements that do not delay its absorption, for instance:

Contents Related to Hydrolyzed Whey Protein:

Flavor - 100%

Easy Digestion - 100%

Protein Source - 100%

Price/Quality - 100%


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About Melanie Ramos
Melanie Ramos
Melanie Ramos uses the HSN Blog to share the latest information and content, so that all those readers who want to learn.
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